The discovery of the RAS oncogene in the 1960s has led to whole new scientific fields devoted to understanding how gene mutations underlie the development of cancer and how complex multi-protein pathways carefully regulate cellular proliferation. A recent structural study provided proof-of-concept evidence that it may be possible to inhibit two RAS isoforms with one inhibitor.

Materials assembled from nanoparticles offer a promising pathway toward engineered materials with revolutionary functional properties. Researchers have demonstrated a generalized approach for engineering open superlattices, which are structures wherein each NP maintains a low coordination number, meaning a small number of neighbors.

Scientists have shown they can use inert gases other than argon to improve the microstructure of the parts and reduce defects in additive manufacturing. New research has uncovered an explanation for why different gases may generate different results.

One promising option for a low-carbon alternative to cement is alkali-activated slag. The latest research found that both high- and low-magnesium alkali-activated slag samples formed mostly amorphous calcium carbonate after aggressive CO₂ exposure, rather than the crystalline calcite that often forms in Portland cement.

The long-term thermal stability of structural alloys is critical to the safe and reliable operation of nuclear reactors. Laser powder bed fusion (LPBF) is a type of additive manufacturing that fuses thin layers of metal powders into net-shape components. However, unlike conventional wrought stainless-steel components that have a long track record of thermal stability, knowledge about thermally induced changes in LPBF components is sparse. A research team used the APS to address this knowledge gap.